Table 4 Multivariate Cox regression analysis for outcome death after transplantation
Hazard ratio | 95% CI | p-value | |
|---|---|---|---|
Multivariate model with CD4/CD8 ratio | |||
Male sex | 0.36 | 0.16–0.78 | 0.011 |
Age at transplantation (per year) | 1.07 | 1.03–1.11 | <.001 |
Pre-emptive transplantation (no dialysis) | 0.25 | 0.09–0.70 | 0.008 |
Cardiovascular disease prior to transplantation | 2.19 | 0.92–4.45 | 0.08 |
Log C-reactive protein (mg/ml) | 1.82 | 0.83–3.97 | 0.134 |
CD4/CD8 ratio | 0.57 | 0.37–0.86 | 0.008 |
Multivariate model with CMV serostatus | |||
Male sex | 0.40 | 0.18–0.86 | 0.02 |
Age at transplantation (per year) | 1.06 | 1.02–1.1 | 0.001 |
Pre-emptive transplantation (no dialysis) | 0.26 | 0.10–0.74 | 0.010 |
Cardiovascular disease prior to transplantation | 1.76 | 0.81–3.81 | 0.152 |
Log C-reactive protein (mg/ml) | 2.11 | 0.96–4.66 | 0.064 |
CMV positive serostatus | 1.14 | 0.53–2.46 | 0.73 |
Multivariate model with naïve CD4 T cells | |||
Male sex | 0.29 | 0.28–0.66 | 0.036 |
Age at transplantation (per year) | 1.06 | 1.02–1.09 | 0.002 |
Pre-emptive transplantation | 0.25 | 0.09–0.68 | 0.006 |
Cardiovascular disease prior to transplantation | 1.57 | 0.70–3.50 | 0.27 |
Log C-reactive protein (mg/ml) | 1.81 | 0.83–4.84 | 0.036 |
Naive CD4 T cells (per cell/ul) | 0.99 | 0.98–0.99 | < 0.001 |
Multivariate model with naïve CD8 T cells | |||
Male sex | 0.42 | 0.19–0.92 | 0.030 |
Age at transplantation (per year) | 1.04 | 0.99–1.07 | 0.056 |
Pre-emptive transplantation | 0.26 | 0.09–0.68 | 0.005 |
Cardiovascular disease prior to transplantation | 1.61 | 0.77–3.48 | 0.22 |
Log C-reactive protein (mg/ml) | 2.09 | 1.01–4.33 | 0.115 |
Naive CD8 T cells (per cell/ul) | 0.98 | 0.96–0.99 | 0.006 |