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Table 2 Analysis of the obesity-associated risk for aging-related diseases

From: First evidence for STING SNP R293Q being protective regarding obesity-associated cardiovascular disease in age-advanced subjects – a cohort study

Diseases (N: cases/controls)

P-value

OR (95%CI)

Aging-related diseases (2009/810)*

< 0.001

1.595 (1.323–1.925)

Cardiovascular disease (382/810)

0.015

1.405 (1.068–1.846)

Chronic lung disease (160/810)

0.018

1.579 (1.081–2.307)

Cancer (47/810)

0.362

0.709 (0.338–1.486)

DM-T2 (177/810)

< 0.001

2.359 (1.667–3.338)

Cognitive impairment (343/810)

0.181

1.238 (0.905–1.694)

  1. Analysis was done by logistic regression using SPSS Statistic software package (version 20.0 IBM, Munich, Germany) with BMI < 30 kg/m2 as reference and BMI ≥30 kg/m2 as predictor, and was corrected for age, sex and former smoking. * 60 samples were excluded from the analysis due to the incomplete disease record