Table 2 Adjusted hazard ratios of overall survival
Variable | Aged between 60 and 79 years | Aged more than 80 years | ||||
|---|---|---|---|---|---|---|
HR | (95%CI) | p-value | HR | (95%CI) | p-value | |
Frontline treatment | ||||||
R-CHOP | 1 | < 0.0001 | 1 | 0.0003 | ||
R-CVP | 1.65 | (1.44–1.89) | 1.48 | (1.22–1.80) | ||
CHOP | 1.81 | (1.44–2.28) | 1.37 | (0.85–2.21) | ||
CVP | 3.08 | (2.33–4.08) | 1.65 | (1.19–2.29) | ||
Gender | ||||||
male | 1 | 0.0004 | 1 | 0.5606 | ||
female | 0.82 | (0.73–0.91) | 0.95 | (0.79–1.14) | ||
Age | 1.03 | (1.02–1.05) | < 0.0001 | 1.05 | (1.02–1.07) | 0.0001 |
Ann Arbor stage | ||||||
I | 1 | < 0.0001 | 1 | < 0.0001 | ||
II | 1.32 | (1.07–1.62) | 1.24 | (0.92–1.68) | ||
III | 2.07 | (1.69–2.55) | 1.53 | (1.14–2.04) | ||
IV | 3.06 | (2.52–3.70) | 2.19 | (1.66–2.90) | ||
Radiotherapy | ||||||
No | 1 | 0.0067 | 1 | 0.5483 | ||
Yes | 1.21 | (1.06–1.39) | 1.07 | (0.85–1.35) | ||
Carlson comorbidity index | ||||||
0 | 1 | < 0.0001 | 1 | 0.7487 | ||
1 | 1.09 | (0.95–1.26) | 0.94 | (0.75–1.18) | ||
2+ | 1.43 | (1.25–1.64) | 1.02 | (0.82–1.26) | ||
Practice setting | ||||||
medical center | 1 | 0.0130 | 1 | 0.5251 | ||
others | 1.16 | (1.03–1.30) | 1.06 | (0.88–1.28) | ||