Table 2 Mean levels of inflammatory markers and complement pathway components in young and old adults
Young* | Old * | P-value | |
|---|---|---|---|
CRP (mg/L) | 2.37 (2.16) | 2.60 (1.91) | 0.671 |
IL-6 (pg/ml) | 1.59 (1.10) | 2.46 (1.44) | 0.013 |
TNF-α (pg/ml) | 1.02 (0.266) | 1.26 (0.42) | 0.013 |
CH50 (U/mL) | 69.13 (16.25) | 74.10 (15.86) | 0.249 |
C1q (units/ml) | 722.7 (84.3) | 651.4 (82.1) | 0.002 |
C3 (mg/dL) | 131.8 (22.3) | 121.1 (26.1) | 0.102 |
C4 (mg/dL) | 27.40 (8.62) | 25.70 (6.92) | 0.420 |
MBL (ng/ml) | 1650 (1251) | 1889 (1541) | 0.520 |
MBL (% activity) | 45.37 (39.41) | 53.78 (39.23) | 0.424 |
CL-L1 (ng/ml) | 486.2 (71.8) | 482.8 (80.6) | 0.866 |
MASP-1 (ng/ml) | 12,117 (2838) | 11,539 (3492) | 0.493 |
MASP-2 (ng/ml) | 600.1 (366.2) | 507.6 (171.8) | 0.236 |
MASP-3 (ng/ml) | 7184 (1943) | 7481 (2097) | 0.580 |
MAp 44 (ng/ml) | 2127 (519) | 2166 (423) | 0.758 |
MAp 19 (ng/ml) | 372.6 (85.2) | 360.1 (96.4) | 0.604 |
H-ficolin (ng/ml) | 24,091 (9085) | 27,370 (5889) | 0.116 |
M-ficolin (ng/ml) | 3500 (1195) | 3813 (1056) | 0.304 |
L-ficolin (ng/ml) | 3044 (1403) | 3314 (995) | 0.403 |