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Table 1 Baseline characteristics of the study population

From: The age again in the eye of the COVID-19 storm: evidence-based decision making

Clinical and demographic characteristics All patients n = 257; (%)
Severity
 Mild 37 (14.4)
 Moderate 139 (54.1)
 Severe 81 (31.5)
Sex
 Male 148 (57.6)
 Female 109 (42.4)
Hypertension 121 (49.2)
ACEIa intake
 No 74 (67.9)
 Yes 35 (32.1)
ARBa intake
 No 74 (67)
 Yes 36 (33)
Dyslipidaemia 102 (41.6)
Statins intake
 No 57 (52.8)
 Yes 51 (47.2)
Diabetes 68 (27.6)
Obesity 34 (16.9)
Primary Immunodeficiency 2 (0.9)
Secondary Immunodeficiency 41 (18.1)
Epidemiological background
 Nursing home resident 36 (22.5)
 Live-in relative 52 (35.5)
 Frontline worker 14 (8.8)
 Community transmission 42 (26.3)
  Ref.vb n Mean Median SDc IQRd
Age   257 66.0 68.0 17.0 54–90
Laboratory data on admission
 IL6e (pg/mL) < 4.4 139 62.2 29.9 94.4 10–296.6
 CRPf (mg/L) < 10 242 105 47 246 10.8–324.6
 Ferritin (ng/mL) 20–250 197 882 499 111 211–2718
 D-dimer (ng/mL) < 500 237 2532 741 10,683 410–6258
 LDHg (U/L) 120–246 234 336 289 168 212–681
 Days from onset to admission   240 8 7 5 4–16
 Leucocyte count (cells*103/μL) 4–12.4 252 8.31 6.60 7.99 4.90–17.60
 Neutrophil count (cells*103/μL) 1.9–8 252 6.20 5.06 4.14 3.26–15.07
 Lymphocyte count (cells*103/μL) 0.9–5 252 2.18 1.00 10.75 0,7-2,59
 Lymphocyte % 19–48 232 17.30 14.50 12.00 9.5–40.3
 CD3 + CD4+ % 25–65 76 44.20 45.80 13.20 36.6–67.9
 CD3 + CD4+ count (cells*106/μL) 500–1400 75 541 460 365 257–1263
 CD3 + CD8+ % 12–40 76 21.70 21.10 10.50 14.5–40
 CD4 + CD8+ count (cells*106/μL) 250–1000 75 268 182 234 117–685
 CD19+ % 5–20 68 14.20 13.30 8.30 8.1–32.8
 CD19+ count (cells*106/μL) 100–500 67 164 127 151 66–409
 Natural Killer % 5–20 68 16.30 14.40 9.00 9–36.8
 Natural Killer count (cells*106/μL) 50–500 64 171 148 107 103–335
 Immunoglobulin G (mg/dL) 650–1600 60 961.0 924.0 431.0 728–1629
 Immunoglobulin A (mg/dL) 40–350 60 264.0 228.0 152.0 162–587
 Immunoglobulin M (mg/dL) 50–300 60 105.0 89.0 83.0 70–256
 C3 (mg/dL)   71 133.0 127.0 46.0 108–225
 C4 (mg/dL)   70 30.0 28.0 13.0 23–56
 Total days in hospital   245 16 12 11 7–38
  1. Abbreviations: RASBa Renin-angiotensin system blockers, Ref.vb Reference values, SDc Standard deviation, IQRd Interquartile range, IL6e Interleukin 6, CRPf C-reactive protein, LDHg Lactate dehydrogenase