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Table 4 Age and Laboratory results by COVID-19 severity

From: The age again in the eye of the COVID-19 storm: evidence-based decision making

 

Severity p-value

n

Mean

Median

SDa

IQRb

Age

0.002

     

 Mild

 

37

68.22

68

16.64

54–82

 Moderate

 

138

62.87

66

16.84

49.32–76

 Severe

 

80

70.59

70

13.19

61.5–80.5

On admission

 IL6c (pg/mL)

< 0.001

     

  Mild

 

11

25.01

10.6

32.31

5.2–37.1

  Moderate

 

88

44.85

29.46

56.46

8.41–56.5

  Severe

 

40

110.47

43.45

143.75

20.05–143.62

 CRPd (mg/L)

0.006

     

  Mild

 

34

43.87

22.35

54.88

8.16–58.4

  Moderate

 

135

80.74

37.8

200.46

6.8–103.75

  Severe

 

73

177.13

100.6

344.21

43.3–195.3

 Ferritin (ng/mL)

0.002

     

  Mild

 

22

474.00

256.8

540.30

197–535

  Moderate

 

120

731.87

459.75

907.18

181–925

  Severe

 

55

1373.10

929

1488.30

366.4–1805

 D-dimer (ng/mL)

  Mild

 

30

1234.90

684

2069.30

373–1297

  Moderate

 

134

1652.22

715.5

5786.79

431–1150

  Severe

 

73

4680.19

800

17,425.42

462–1990

 LDHe (U/L)

< 0.001

     

  Mild

 

31

215.39

206

62.63

172–243

  Moderate

 

128

328.92

287

160.07

213.5–408.5

  Severe

 

75

396.96

354

183.43

263–507

 Leucocyte count (cells*103/μL)

0.011

     

  Mild

 

34

424.62

6.39

1813.47

5.53–8.78

  Moderate

 

137

190.92

6.37

1098.34

4.6–8.75

  Severe

 

81

280.85

8.25

1441.86

5.5–12.98

 Neutrophil count (cells*103/μL)

  Mild

 

34

286.69

4.85

1244.32

3–6.85

  Moderate

 

137

129.54

4.8

782.33

3.17–7

  Severe

 

81

220.16

7

1147.11

4.19–11.58

 Lymphocyte count (cells*103/μL)

0.005

     

  Mild

 

34

1.44

1.29

0.78

0,84-1,78

  Moderate

 

137

2.1

1.06

9.07

0,7-1,39

  Severe

 

81

1

0.91

0.59

0,68-1,15

 Lymphocyte %

0.005

     

  Mild

 

34

21.92

18.85

12.74

14–28.2

  Moderate

 

119

18.82

15

12.64

10.9–25

  Severe

 

79

13.10

11

9.27

6.6–16.7

 CD3 + CD4+ %

  Mild

 

9

51.17

51

11.79

43.1–56.7

  Moderate

 

48

43.88

45.76

12.71

37.43–51.525

  Severe

 

19

41.78

41

14.46

34.32–52.74

 CD3 + CD4+ count (cells*103/μL)

0.007

     

  Mild

 

9

729.87

565

445.12

372.015–1035

  Moderate

 

48

586.66

516

365.49

289.252–818.5

  Severe

 

18

325.35

293

210.64

185.934–466.519

 CD3 + CD8+ %

  Mild

 

9

20.45

24.4

10.09

14.79–27.1

  Moderate

 

48

21.95

21.84

9.48

14.83–27.05

  Severe

 

19

21.71

18

13.23

12.34–28.9

 CD4 + CD8+ count (cells*103/μL)

0.018

     

  Mild

 

9

263.29

177

205.19

143.616–269.955

  Moderate

 

48

283.92

214

195.35

132.5–412.5

  Severe

 

18

226.03

129.22

331.47

82–228

 CD19+ %

  Mild

 

9

12.08

12.76

5.00

9.8–15.8

  Moderate

 

44

13.98

13.47

7.91

7.4–17.18

  Severe

 

15

16.16

14.5

10.81

9–20.68

 CD19+ count (cells*103/μL)

  Mild

 

9

166.59

145

108.67

76.23–241.74

  Moderate

 

44

177.19

130

168.64

66.5–217.966

  Severe

 

14

120.52

114.85

108.90

66–132.936

 Natural Killer %

  Mild

 

9

12.91

11

6.85

7.7–15

  Moderate

 

44

16.85

14.63

9.24

9.205–20.75

  Severe

 

15

16.93

17.06

9.66

8.36–23.8

 Natural Killer count (cells*103/μL)

  Mild

 

9

159.68

132

89.67

103–169

  Moderate

 

41

188.59

157

116.15

119–223

  Severe

 

14

126.01

127.9

75.10

66–188

 IgG (mg/dL)

  Mild

 

9

853.84

918

212.83

782–980

  Moderate

 

31

981.27

950.3

296.30

772.14–1190

  Severe

 

20

976.96

821

642.17

618.255–1048.5

 IgA (mg/dL)

  Mild

 

9

284.40

239

206.15

175–277

  Moderate

 

31

278.63

251

133.13

184.85–358

  Severe

 

20

232.88

189.97

154.48

152.5–311

 IgM (mg/dL)

0.009

     

  Mild

 

9

164.57

94

175.42

86.3–133

  Moderate

 

31

103.63

98.7

53.67

71.59–132

  Severe

 

20

81.39

84

43.07

46.45–112.95

 C3 (mgdL)

  Mild

 

8

142.80

139

25.72

125–151.68

  Moderate

 

38

135.03

127

50.55

108–152

  Severe

 

25

126.91

125

44.84

90–153.28

 C4 (mgdL)

  Mild

 

8

31.58

29.5

5.26

28.4–33.85

  Moderate

 

37

30.52

29.3

11.72

23–39

  Severe

 

25

28.30

25.7

15.40

23–29.8

  1. Abbreviations: SDa Standard deviation, IQRb Interquartile range, IL6c Interleukin 6, CRPd C-reactive protein, LDHe Lactate dehydrogenase
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Immunity & Ageing

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