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Table 4 Age and Laboratory results by COVID-19 severity

From: The age again in the eye of the COVID-19 storm: evidence-based decision making

  Severity p-value n Mean Median SDa IQRb
Age 0.002      
 Mild   37 68.22 68 16.64 54–82
 Moderate   138 62.87 66 16.84 49.32–76
 Severe   80 70.59 70 13.19 61.5–80.5
On admission
IL6c (pg/mL) < 0.001      
  Mild   11 25.01 10.6 32.31 5.2–37.1
  Moderate   88 44.85 29.46 56.46 8.41–56.5
  Severe   40 110.47 43.45 143.75 20.05–143.62
CRPd (mg/L) 0.006      
  Mild   34 43.87 22.35 54.88 8.16–58.4
  Moderate   135 80.74 37.8 200.46 6.8–103.75
  Severe   73 177.13 100.6 344.21 43.3–195.3
Ferritin (ng/mL) 0.002      
  Mild   22 474.00 256.8 540.30 197–535
  Moderate   120 731.87 459.75 907.18 181–925
  Severe   55 1373.10 929 1488.30 366.4–1805
D-dimer (ng/mL)
  Mild   30 1234.90 684 2069.30 373–1297
  Moderate   134 1652.22 715.5 5786.79 431–1150
  Severe   73 4680.19 800 17,425.42 462–1990
LDHe (U/L) < 0.001      
  Mild   31 215.39 206 62.63 172–243
  Moderate   128 328.92 287 160.07 213.5–408.5
  Severe   75 396.96 354 183.43 263–507
Leucocyte count (cells*103/μL) 0.011      
  Mild   34 424.62 6.39 1813.47 5.53–8.78
  Moderate   137 190.92 6.37 1098.34 4.6–8.75
  Severe   81 280.85 8.25 1441.86 5.5–12.98
Neutrophil count (cells*103/μL)
  Mild   34 286.69 4.85 1244.32 3–6.85
  Moderate   137 129.54 4.8 782.33 3.17–7
  Severe   81 220.16 7 1147.11 4.19–11.58
Lymphocyte count (cells*103/μL) 0.005      
  Mild   34 1.44 1.29 0.78 0,84-1,78
  Moderate   137 2.1 1.06 9.07 0,7-1,39
  Severe   81 1 0.91 0.59 0,68-1,15
Lymphocyte % 0.005      
  Mild   34 21.92 18.85 12.74 14–28.2
  Moderate   119 18.82 15 12.64 10.9–25
  Severe   79 13.10 11 9.27 6.6–16.7
CD3 + CD4+ %
  Mild   9 51.17 51 11.79 43.1–56.7
  Moderate   48 43.88 45.76 12.71 37.43–51.525
  Severe   19 41.78 41 14.46 34.32–52.74
CD3 + CD4+ count (cells*103/μL) 0.007      
  Mild   9 729.87 565 445.12 372.015–1035
  Moderate   48 586.66 516 365.49 289.252–818.5
  Severe   18 325.35 293 210.64 185.934–466.519
CD3 + CD8+ %
  Mild   9 20.45 24.4 10.09 14.79–27.1
  Moderate   48 21.95 21.84 9.48 14.83–27.05
  Severe   19 21.71 18 13.23 12.34–28.9
CD4 + CD8+ count (cells*103/μL) 0.018      
  Mild   9 263.29 177 205.19 143.616–269.955
  Moderate   48 283.92 214 195.35 132.5–412.5
  Severe   18 226.03 129.22 331.47 82–228
CD19+ %
  Mild   9 12.08 12.76 5.00 9.8–15.8
  Moderate   44 13.98 13.47 7.91 7.4–17.18
  Severe   15 16.16 14.5 10.81 9–20.68
CD19+ count (cells*103/μL)
  Mild   9 166.59 145 108.67 76.23–241.74
  Moderate   44 177.19 130 168.64 66.5–217.966
  Severe   14 120.52 114.85 108.90 66–132.936
Natural Killer %
  Mild   9 12.91 11 6.85 7.7–15
  Moderate   44 16.85 14.63 9.24 9.205–20.75
  Severe   15 16.93 17.06 9.66 8.36–23.8
Natural Killer count (cells*103/μL)
  Mild   9 159.68 132 89.67 103–169
  Moderate   41 188.59 157 116.15 119–223
  Severe   14 126.01 127.9 75.10 66–188
IgG (mg/dL)
  Mild   9 853.84 918 212.83 782–980
  Moderate   31 981.27 950.3 296.30 772.14–1190
  Severe   20 976.96 821 642.17 618.255–1048.5
IgA (mg/dL)
  Mild   9 284.40 239 206.15 175–277
  Moderate   31 278.63 251 133.13 184.85–358
  Severe   20 232.88 189.97 154.48 152.5–311
IgM (mg/dL) 0.009      
  Mild   9 164.57 94 175.42 86.3–133
  Moderate   31 103.63 98.7 53.67 71.59–132
  Severe   20 81.39 84 43.07 46.45–112.95
C3 (mgdL)
  Mild   8 142.80 139 25.72 125–151.68
  Moderate   38 135.03 127 50.55 108–152
  Severe   25 126.91 125 44.84 90–153.28
C4 (mgdL)
  Mild   8 31.58 29.5 5.26 28.4–33.85
  Moderate   37 30.52 29.3 11.72 23–39
  Severe   25 28.30 25.7 15.40 23–29.8
  1. Abbreviations: SDa Standard deviation, IQRb Interquartile range, IL6c Interleukin 6, CRPd C-reactive protein, LDHe Lactate dehydrogenase