Fig. 3
From: Loss of toll-like receptor 4 ameliorates cardiovascular dysfunction in aged mice
Effects of loss of TLR4 on cardiac function and senescence. A Heart weight/tibia length ratio of young, aged and TLR4−/− aged mice. B Ejection fraction of mice in different groups. C and D Left ventricular end-diastolic diameter (LVIDd) and isovolumic relaxation time (IVRT) of mice in different groups. E Representative Western blots of p16 and p53 in the hearts of mice in different groups. F Statistical results of p16 and p53 in hearts. n = 6 for each group. ns, not significant. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001