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Table 1 Characteristics of the study population stratified by gender at baseline

From: Association of immunity markers with the risk of incident frailty: the Rugao longitudinal aging study

Characteristics

 

Total (N = 1822)

Males (n = 848)

Females (n = 974)

P-value

Age

M ± SD, years

78.03 ± 4.46

77.92 ± 4.44

78.13 ± 4.47

0.300

Body mass index

M ± SD, kg/m2

24.14 ± 6.04

23.86 ± 3.31

24.39 ± 7.65

0.062

Smoking Ç‚

Yes, n (%)

365 (20.03%)

327 (38.56%)

38 (3.90%)

<  0.001

No, n (%)

1440 (79.03%)

510 (63.80%)

930 (95.48%)

 

Alcohol assumption Ç‚

Yes, n (%)

553 (29.25%)

381 (44.93%)

172 (17.66%)

<  0.001

No, n (%)

1246 (68.39%)

453 (53.42%)

793 (81.41%)

 

Educational status Ç‚

Illiteracy

879 (48.24%)

148 (17.45%)

731 (75.05%)

<  0.001

Non-illiteracy

942 (51.70%)

699 (82.43%)

243 (24.95%)

 

Marital status&, Ç‚

Married, n (%)

1171 (64.27%)

627 (73.94%)

544 (55.85%)

<  0.001

Others &, n (%)

607 (33.32%)

201 (23.70%)

406 (41.68%)

 

Regular exercise Ç‚

Yes, n (%)

412 (22.61%)

238 (28.07%)

174 (17.86%)

<  0.001

No, n (%)

1237 (67.56%)

531 (62.62%)

706 (72.48%)

 

Triglyceride

M ± SD, mmol/L

1.42 ± 1.01

1.22 ± 0.88

1.59 ± 1.09

<  0.001

High-density lipoprotein

M ± SD, mmol/L

1.85 ± 0.45

1.84 ± 0.45

1.86 ± 0.46

0.371

Low-density lipoprotein

M ± SD, mmol/L

2.80 ± 0.63

2.70 ± 0.61

2.88 ± 0.64

<  0.001

Fasting blood glucose

M ± SD, mmol/L

5.83 ± 1.50

5.73 ± 1.36

5.92 ± 1.60

0.006

Neutrophil count

M ± SD, ×109/L

3.53 ± 1.36

3.65 ± 1.42

3.43 ± 1.29

0.001

Lymphocytes count

M ± SD, × 109/L

2.05 ± 0.94

2.00 ± 1.11

2.09 ± 0.77

0.036

Platelet count

M ± SD, × 109/L

190.57 ± 67.78

182.11 ± 61.25

197.97 ± 72.22

<  0.001

NLR

M ± SD

1.97 ± 1.12

2.12 ± 1.27

1.84 ± 0.96

<  0.001

PLR

M ± SD

104.26 ± 50.56

103.01 ± 50.05

105.37 ± 51.01

0.319

SII

M ± SD

378.13 ± 295.56

389.32 ± 306.74

368.56 ± 285.39

0.135

Self-report hypertension

Yes, n (%)

848 (46.54%)

371 (43.75%)

477 (48.97%)

0.015

No, n (%)

974 (53.46%)

477 (56.25%)

497 (51.03%)

0.265

Comorbidity Ŧ

Yes, n (%)

341 (18.72%)

153 (18.04%)

188 (19.30%)

0.269

No, n (%)

1481 (81.28%)

695 (81.96%)

786 (80.70%)

 

Frailty status at baseline

Robust, n (%)

583 (32.00%)

333 (39.27%)

250 (25.66%)

<  0.001

Pre-Frailty, n (%)

1039 (57.02%)

452 (53.30%)

587 (60.27%)

 

Frailty, n (%)

200 (10.98%)

63 (7.43%)

137 (14.07%)

 
  1. M: mean, SD: standard deviation. NLR: neutrophil-to-lymphocytes ratio, PLR: platelet-to-lymphocyte ratio, SII: systemic immune-inflammation index, Continuous and categorical variables were present as mean with SD and frequency (%), Group difference were analyzed by chi-square or ANOVA test. & including separated, divorced, never married or widowed. ǂ Unknown: Educational status (1, 0.05%), Marital status (44, 2.41%), Alcohol assumption (23, 1.26%), Smoking: (17, 0.93%), Regular exercise: (173, 9.50%). Ŧ Including cerebral infarction, stroke, cerebral hemorrhage, coronary heart disease, myocardial infarction, heart failure and cancer
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Immunity & Ageing

ISSN: 1742-4933

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