Association between immunoglobulin A and depression in Chinese older adults: findings from a cross-sectional study

Table 2 Multiple linear regression analyses between immunoglobulins and GDS-15

Variables	Beta	95% CI	P
Immunoglobulin A
Model 1	0.118	0.032–0.203	0.007
Model 2	0.102	0.019–0.185	0.016
Model 3	0.106	0.016–0.195	0.020
Immunoglobulin G
Model 1	0.030	-0.010–0.069	0.140
Model 2	0.000	-0.038–0.038	0.988
Model 3	-0.011	-0.052–0.029	0.585
Immunoglobulin M
Model 1	-0.271	-0.500- -0.042	0.020
Model 2	-0.248	-0.469- -0.027	0.028
Model 3	-0.315	-0.569- -0.061	0.015
Immunoglobulin E
Model 1	0.000	-0.005–0.005	0.924
Model 2	-0.001	-0.006–0.003	0.580
Model 3	-0.003	-0.008–0.002	0.253
Complement C3
Model 1	-0.008	-0.015- -0.002	0.009
Model 2	-0.002	-0.008–0.004	0.567
Model 3	-8.82E-5	-0.008–0.007	0.982
Complement C4
Model 1	-0.012	-0.028–0.005	0.159
Model 2	0.004	-0.012–0.021	0.595
Model 3	0.004	-0.015–0.023	0.669

Notes: Model 1: no adjustment; Model 2: adjusted for age, sex, and ethnicity; Model 3: age, sex, ethnicity, centenarians, SBP, DBP, RBC, hemoglobin, MCHC, WBC, neutrophil, CRP, immunoglobulin A, immunoglobulin G, immunoglobulin M, immunoglobulin E, complement C3, and complement C4
Abbreviations: CI Confidence interval, SBP Systolic blood pressure, DBP Diastolic blood pressure, RBC Red blood cell, MCHC Mean corpuscular hemoglobin concentration, WBC White blood cell, CRP C-reactive protein

ISSN: 1742-4933