Fig. 2
From: Excessive IL-15 promotes cytotoxic CD4 + CD28− T cell-mediated renal injury in lupus nephritis
CD4 + CD28− T cell filtration is correlated with the clinicopathological characteristics of LN patients
(A) Staining for CD3, CD4 and CD28 performed on SLE kidney slides showed that most infiltrating CD4 + T cells did not express CD28. Arrows point to CD3 + CD4 + CD28−T cells
(B-E) Correlation between the CD4 + CD28− T cell population and clinicopathological characteristics in 35 LN IV patients: B, negative correlation with GFR; C-E, positive correlation with chronicity index, proteinuria and glomerulosclerosis