Table 1 Clinical and demographic characteristics of SLE/LN patients and healthy controls
From: Excessive IL-15 promotes cytotoxic CD4 + CD28− T cell-mediated renal injury in lupus nephritis
Category | Features | SLE without nephritis (n = 10) | SLE with nephritis (n = 82) | Healthy donors(n = 36) |
|---|---|---|---|---|
Demographic | Age (mean ± SD) | 38.7 ± 11.3 | 32.9 ± 12.0 | 34.9 ± 11.2 |
Female (%) | 100 | 96.2 | 100 | |
Asian (%) | 100 | 100 | 100 | |
Disease activity | SLEDAI (mean ± SD) | 8.27 ± 4.10 | 10.26 ± 4.36 | |
Anti-dsDNA antibody (n, %) | 6 (54.5) | 39 (48.1) | ||
C3 complement (g/L, mean ± SD) | 0.44 ± 0.20 | 0.53 ± 0.26 | ||
Medication | Naive (n, %) | 7 (63.6) | 44 (54.3) | |
Prednisone, currently taking (n, %) | 4 (36.3) | 37 (45.6) | ||
Hydroxychloroquine (%) | 4 (36.3) | 30 (37.0) | ||
Mycophenolate Mofetil exposure (%) | 2 (18.1) | 12 (14.8) | ||
Cyclophosphamide exposure (%) | 1 (9.1) | 16 (12.5) |