Fig. 2
From: Inflammation and cell-to-cell communication, two related aspects in frailty
IL-1β plasma levels significantly increase with frailty. (A) IL-1β plasma levels are significantly higher in all Frail (Fr, n = 65) compared to nFr (n = 64) subjects (*p < 0.05). IL-1β plasma levels were analyzed according to gender separation; in (B) IL-1β plasma levels in Fr male (n = 33) do not change compared to nFr male (n = 32) subjects. In (C) are reported data from Fr female (n = 32) compared to nFr female (n = 32) subjects, a statistically significant increase is observed in Fr vs. nFr subjects (**p < 0.01). Statistical analysis was performed using the Mann–Whitney U test (non-parametric) for comparisons between two groups using GraphPad Prism8 software. A p < 0.05 was considered statistically significant