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Table 1 Results of CRP analysis and cytokine detection by the Meso Scale Discovery (MSD), in Fr (n = 65) and nFr (n = 63) subjects. The median value, 25th (Q1) and 75th (Q3) percentile values and the p-value in the Fr and nFr group were reported

From: Inflammation and cell-to-cell communication, two related aspects in frailty

 

nFr

Fr

p-value

Median

Q1

Q3

Median

Q1

Q3

CRP

0,115

0,06

0,182

0,245

0,11

0,56

 < 0.0001

IFNγ

4,742

2,667

8,021

5,079

3,358

6,981

0,4331

IL-10

0,248

0,177

0,312

0,254

0,169

0,423

0,3323

IL-12p70

0,12

0,079

0,164

0,148

0,078

0,201

0,1645

IL-13

1,2

0,648

2,498

2,032

0,852

3,213

0,0852

IL-1β

0,028

0,018

0,042

0,047

0,028

0,167

0,0108

IL-2

0,139

0,088

0,193

0,153

0,099

0,207

0,2116

IL-4

0,019

0,007

0,038

0,018

0,01

0,035

0,9706

IL-6

0,515

0,401

0,653

1,087

0,734

1,5

 < 0.0001

IL-8

3,12

2,325

3,728

3,316

2,387

4,914

0,1091

TNFα

1,92

1,5

2,144

2,337

1,836

2,693

0,0006

  1. Fr Frail, nFr non-Frail, Q1 25th percentile, Q3 75th percentile, CRP C-reactive protein, IFNγ interferon, IL-10 interleukin-10, IL-12p70 interleukin-12p70, IL-13 interleukin-13, IL-1β interleukin-1β, IL-2 interleukin-2, IL-4 interleukin-4, IL-6 interleukin-6, IL-8 interleukin-8, TNFα tumor necrosis factor α