Fig. 2

Colocalization of tau deposits with syndecan-2. Brains were collected after completion of behavioral analysis and stained for syndecan-2 (red) and tau (green). Representative images of hippocampus and entorhinal cortex collected with 40X (A) and 63X (B) objectives show close apposition of tau deposits and syndecan-2 with partial overlap (yellow). Scale bar in (A) 50 μm and in (B) 25 μm. Syndecan-2 staining reduces along with the reduction in tau clustering in brains from mice treated with MSC after completion of cisplatin treatment.