Skip to main content

Table 2 Differences in PC scores and Euclidean distance (in the space defined by PC1 and PC2) between treatments and control (untreated cells) for costimulatory molecule expression. We observe a cluster of adjuvants (MPLA, LPS, CpG, and NP + Mi + CpG) that suggest greater upregulation of costimulatory molecule expression than the other adjuvants

From: “Just right” combinations of adjuvants with nanoscale carriers activate aged dendritic cells without overt inflammation

Adjuvants

PC1(Adjuv)-PC1(Media)

PC2(Adjuv)-PC2(Media)

Distance(PC1,PC2)

NP

0.32

−0.45

0.55

CDN

0.42

−0.61

0.74

Micelles

−0.1

−0.82

0.82

FLA-BS

1.1

−0.51

1.21

NP + Mi + CDN

2.18

−0.15

2.19

MDP

1.81

−1.69

2.47

R848

2.32

−0.97

2.52

NP + Mi + R848

2.76

0.29

2.78

MPLA

3.54

−0.09

3.54

LPS

3.65

−0.19

3.66

CpG

3.95

−0.58

4.00

NP + Mi + CpG

4.25

−0.44

4.27