Table 1 Linear regression multivariable analyses of the magnitude of the initial response to the vaccine one month after the second dose of the BNT162B2 vaccine (T1) and loss of anti-S IgG titers at the short- (T1-T4) and long-term (T1-T8)
Parameter | β coefficient (95% CI) | p |
|---|---|---|
Anti-S antibody titers (T1) | ||
Age (years) | −0.512 (− 0.021 to 0.001) | 0.100 |
Albumin (g/dL) | 0.134 (− 0.197 to 0.434) | 0.455 |
Total IgM (mg/dL) | 0,1185 (−0.001 to 0.002) | 0.599 |
Total IgG (mg/dL) | 0.189 (0.000 to 0.001) | 0.295 |
Folate (ng/mL) | −0.068 (− 0.483 to 0.365) | 0.062 |
Calcium (mg/dL) | 0.030 (−0.213 to 0.256) | 0.855 |
Homocysteine (mg/L) | −0.155 (− 0.241 to − 0.068) | 0.001 |
β2-microglobulin (mg/L) | 0.264 (− 0.012 to 0.162) | 0.089 |
hsCRP (mg/L) | − 0.085 (− 0.026 to 0.013) | 0.502 |
CD3 (cells/μL) | − 0.039 (0.000 to 0.000) | 0.753 |
B cells (cells/μL) | 0.142 (0.000 to 0.002) | 0.257 |
Short-term loss of anti-S antibody titers (T1-T4) | ||
Total IgA (mg/dL) | 0.010 (−0.012 to 0.031) | 0.373 |
Total IgM (mg/dL) | −0.020 (− 0.055 to 0.015) | 0.253 |
hsCRP (mg/L) | 0.440 (−0.368 to 1.248) | 0.280 |
Thymosin-α1 (ng/mL) | −0.168 (− 0.305 to − 0.031) | 0.017 |
sj/β-TRECs ratio | − 0.558 (−1.118 to 0.002) | 0.074 |
Long-term loss of anti-S antibody titers (T1-T8) | ||
Total IgM (mg/dL) | −0.017 (− 0.037 to 0.003) | 0.089 |
Thymosin-α1 (ng/mL) | − 0.123 (− 0.212 to − 0.034) | 0.008 |