Fig. 4
From: Age-related neuroimmune signatures in dorsal root ganglia of a Fabry disease mouse model
Age-depended morphological alteration of male GlaKO DRG macrophages. A Representative images of macrophage morphology based on IBA-1 staining. Scale bar 10 µm. B Representative 3D reconstruction of GlaKO DRG macrophages compared to control. C Filament tracing and D surface reconstruction of macrophages from 28 and 57w old mice. Between 12 and 30 cells per condition were analyzed using Imaris 9.7 with Filaments and Surfaces tools. Statistical significance was assessed using Kruskal–Wallis test followed by pairwise comparisons using Wilcoxon rank sum exact test and Bonferroni correction. Values are given as mean ± SEM. * p < 0.05, ** p < 0.01, *** p < 0.001, if not otherwise stated