Fig. 4

At least 1 cytokine production in total and memory populations of T lymphocytes. Bar graphs represent percentage of at least 1 cytokine production in total CD4 TLs and total CD8 TLs (A.1 and A.2). Bar graphs describe the percentage of at least 1 cytokine production in memory populations includes central memory T-cells (CM), effector memory T-cells (EM) and terminally differentiated effector memory T cells (TEMRA)for CD4 and CD8 T cells in < 40-years group (B.1 and B.2) and for CD4 and CD8 T cells in > 65-years group (C.1 and C.2). The medians with the interquartile ranges are shown. Ex-vivo: Ex-vivo condition; UT: Untreated condition; α1Thy: α1Thy treated condition; SARS-CoV2: SARS-CoV2 peptides stimulation condition; α1Thy + SARS-CoV2: α1Thy treated and SARS-CoV2 peptides stimulation condition. Each dot represents an individual. Orange dots represent < 40 years (n = 18) and > 65 years (n = 16) are highlighted with blue dots. Memory populations represented in green (CM), in violet (EM) and in rose (TEMRA). Wilcoxon test was used comparing condition in the same group and U-Mann Whitney test was used comparing condition between different group (ns: not statistically significative, θ: p > 0.05 and < 0.1 *p < 0.05; **p < 0.01; ***p < 0.001)