Fig. 3

Association between physiological stress load and naïve and memory Tregs. Frequency of (A) naïve Tregs and (C) memory Tregs grouped by subject age. Statistical analysis was performed using Kruskal-Wallis non-parametric one-way ANOVA; ***P < 0.001. Not age-adjusted and age-adjusted linear regression of (B) naïve Treg frequencies and (D) memory Treg frequencies and physiological stress load. Equation, correlation squared (R²), P value for the association constant, and number of subjects are shown for each linear regression