Fig. 4
Association between physiological stress load and frequencies of HLA-DR + Tregs. (A) Frequency of HLA-DR + Tregs grouped by subject age. Statistical analysis was performed using Kruskal-Wallis non-parametric one-way ANOVA; ***P < 0.001. (B) Not age-adjusted and age-adjusted linear regression of HLA-DR + Treg frequencies and physiological stress load. Relationships between subject age and (C) HLA-DR + memory Tregs and (D) memory Tregs. Black lines indicate the linear line of best fit and red indicates the 95% confidence bands of the best-fit line. Equation, correlation squared (R2), P value for the association constant, and number of subjects are shown for each linear regression