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Fig. 3 | Immunity & Ageing

Fig. 3

From: Microglia preserve visual function in the aging retina by supporting retinal pigment epithelial health

Fig. 3

High density of lipofuscin-like lipid droplets in RPE and SRS microglia in aged mice. A Flat mount images of aged RPE labelled with F-actin (red) and DAPI (blue) showing accumulation of autofluorescent (488 nm wavelength) lipofuscin-like lipid droplets. B TEM imaging reveals numerous lipofuscin-like lipid droplets in aged RPE (green arrows) and accumulation of sub-RPE basal laminar deposits. C Aged microglia, in particular subretinal microglia accumulate high level of autofluorescent (488 nm wavelength) lipofuscin-like lipid droplets. Images were taken from mice aged 35 months

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Immunity & Ageing

ISSN: 1742-4933

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