Fig. 4

DN T cells are present in FRT tissues, are more abundant in the endometrium and show redistribution with aging in a site-dependent manner. Flow cytometry analysis of T cell populations in different anatomical regions of the FRT. A Representative plot of T cell populations in the FRT (EM). B Percentage of DN T cells in endometrium (EM), endocervix (CX) and ectocervix (ECX) from the same patients (n = 13; Friedman test). C Comparison of DN T cell percentages in EM and CX/ECX in premenopausal (pre; EM = 10, CX/ECX = 11) and postmenopausal women (post; EM = 16, CX/ECX = 19). D Correlation between age and percentage of DN T cells in EM (left) and CX/ECX (right) following menopause. Non-parametric paired Friedman (B) and unpaired Kruskal–Wallis (C) test followed by Dunn’s post-test. Spearman test was used in D, and P and r values are indicated when the correlation was significant