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Table 1 Characteristics of the study participants by sex (n = 1,029)

From: Objectively-measured movement behaviors, systemic low-grade inflammation, and plasma neurofilament light chain in older adults: a population-based study

Characteristics

Total sample (n = 1,029)

Men (n = 417)

Women (n = 612)

P-value

Age range (years)

60–88

60–84

60–88

–

Age, years

69.56 (4.47)

69.69 (4.47)

69.47 (4.48)

0.472

Education, n (%)

   

 < 0.001

 Illiterate

378 (36.73)

40 (9.59)

338 (55.23)

 

 Primary school

446 (43.34)

209 (50.12)

237 (38.73)

 

 Middle school or above

205 (19.92)

168 (40.29)

37 (6.05)

 

Alcohol intake, n (%)

   

 < 0.001

 Never

632 (61.42)

71 (17.03)

561 (91.67)

 

 Former

82 (7.97)

75 (17.99)

7 (1.14)

 

 Current

315 (30.61)

271 (64.99)

44 (7.19)

 

Smoking, n (%)

   

 < 0.001

 Never

681 (66.18)

82 (19.66)

599 (97.88)

 

 Former

147 (14.29)

140 (33.57)

7 (1.14)

 

 Current

201 (19.53)

195 (46.76)

6 (0.98)

 

Obesity, n (%)

214 (20.80)

72 (17.27)

142 (23.20)

0.021

APOE ε4 allele, n (%)a

160 (15.55)

64 (15.35)

96 (15.69)

0.758

Stroke, n (%)

133 (12.93)

59 (14.15)

74 (12.09)

0.334

Coronary heart disease, n (%)

211 (20.51)

60 (14.39)

151 (24.67)

 < 0.001

Hypertension, n (%)

731 (71.04)

299 (71.70)

432 (70.59)

0.699

Diabetes, n (%)

158 (15.35)

49 (11.75)

109 (17.81)

0.008

Dyslipidemia, n (%)

247 (24.00)

66 (15.83)

181 (29.58)

 < 0.001

Wear seasons, n (%)

   

0.036

 Spring

167 (16.23)

68 (16.31)

99 (16.18)

 

 Summer

385 (37.41)

153 (36.69)

232 (37.91)

 

 Autumn

398 (38.68)

152 (36.45)

246 (40.20)

 

 Winter

79 (7.68)

44 (10.55)

35 (5.72)

 

Daily ActiGraph wear time, hours

14.17 (1.35)

14.08 (1.38)

14.23 (1.33)

0.117

Daily SB time, hours

8.16 (1.92)

8.84 (1.87)

7.71 (1.81)

 < 0.001

Daily LPA time, hours

4.93 (1.48)

4.37 (1.47)

5.32 (1.36)

 < 0.001

Daily MVPA time, hours

1.08 (0.84)

0.88 (0.69)

1.21 (0.90)

 < 0.001

NfL, pg/ml, median (IQR)

11.98 (6.60)

12.99 (7.29)

11.26 (6.20)

 < 0.001

IL-6, pg/ml, median (IQR)

0.86 (0.68)

0.86 (0.67)

0.85 (0.67)

0.584

IL-8, pg/ml, median (IQR)

17.30 (20.35)

16.21 (17.40)

18.39 (22.28)

0.027

TNF-α, pg/ml, median (IQR)

1.73 (0.59)

1.71 (0.58)

1.74 (0.60)

0.457

ICAM-1, ng/ml, median (IQR)

478.83 (100.52)

466.93 (100.65)

486.92 (99.71)

0.002

  1. Data were mean (SD), unless otherwise specified
  2. Abbreviations: APOE Apolipoprotein E gene, SB Sedentary behavior, LPA Light-intensity physical activity, MVPA Moderate-to-vigorous-intensity physical activity, NfL Neurofilament light chain, IQR Interquartile range, IL-6 Interleukin-6, IL-8 Interleukin-8, TNF-α Tumor necrosis factor alpha, ICAM-1 Intercellular cell adhesion molecule-1
  3. aThere were 13 participants who had missing information on APOE genotype and a dummy variable was created to represent these individuals in the subsequent analyses
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Immunity & Ageing

ISSN: 1742-4933

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