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Table 5 Multivariate logistic regression analyses for SCR in participants with pre-vaccination HAI antibody titer ≥ 40

From: Immunogenicity and safety of quadrivalent influenza vaccine among young and older adults in Tianjin, China: implication of immunosenescence as a risk factor

 

SCR

aOR (95% CI)

P

H1N1 (N = 43)

 Age, years

1.018(0.945–1.096)

0.634

 IV history

0.006(0.000–0.151)

0.002

 Pre-vaccination HAI

0.997(0.987–1.008)

0.662

H3N2 (N = 28)

 Age, years

——

0.889

 IV history

——

0.89

 Pre-vaccination HAI

——

0.973

B/Victoria (N = 34)

 Age, years

0.993(0.921–1.071)

0.862

 IV history

2.486(0.323–19.153)

0.382

 Pre-vaccination HAI

0.976(0.94–1.014)

0.212

B/Yamagata (N = 105)

 Age, years

1.006(0.971–1.041)

0.752

 IV history

0.339(0.129–0.887)

0.028

 Pre-vaccination HAI

0.99(0.978–1.003)

0.126

  1. Abbreviations: N Number of subjects in group, CI Confidence interval, aOR Adjusted odds ratio (adjusted for male sex, number of days after vaccine administration for blood sample collection, and common comorbid conditions including hypertension, hyperlipidemia, and diabetes mellitus), IV history Influenza vaccination history in the previous year, HAI Hemagglutination inhibition antibody titer