Fig. 1
From: Towards a better preclinical cancer model – human immune aging in humanized mice
Human immune cell reconstitution of NIKO mice. A Timeline for engrafting human CD34+ cells and harvesting of blood and organs for analysis. Percentage reconstitution of human immune cells in blood, bone marrow, spleen, lung, liver and thymus of NIKO mice over a course of 52 weeks. mean ± SD are indicated; n = 5. B Proportion of various human immune subsets in the blood, bone marrow, spleen, lung and liver over time. For the thymus, immune cells largely comprised of B and T cells, proportion of subsets as shown. Bars show mean ± SD; n = 5