Fig. 2
From: Towards a better preclinical cancer model – human immune aging in humanized mice
Changes in T cell population as humanized mice aged. A to D Proportion of naïve and memory CD4+ and CD8+ T cell subsets in blood (A), lung (B), spleen (C) and liver (D). Bars show mean ± SD; n = 5. E and F Percentage of CD8+ T cells (E) and CD4.+ T cells (F) that express senescent makers, CD57 and KLRG1, over time. Kruskal–Wallis test was used for significance tests. mean ± SD and significant p values are indicated; n = 5