From: Related factors of renal injury in primary Sjögren's syndrome
Renal injury | P value | ||
---|---|---|---|
progression group (N = 39) | non-progression group (N = 248) | ||
Age (years) | 54.00 (42.00–65.00) | 53.00 (41.00–64.00) | 0. 413 |
Female (n, %) | 37, 94.87 | 232, 93.5 | 0. 510 |
Creatinine (μmol/ L) | 79.50 (74.25–91.80) | 68.95 (61.50–77.85) | < 0.001 |
eGFR change (%) | -23.64 (-31.25–-20.42) | 4.71(-1.21–13.14) | < 0.001 |
Urea (mmol/L) | 5.93 (4.80–7.49) | 4.96 (4.07–5.96) | < 0.007 |
Potassium (mmol/L) | 4.00 (3.68–4.31) | 4.00 (3.74–4.25) | 0. 942 |
Sodium (mmol/L) | 141.20 (138.18–144.00) | 141.10 (139.00–143.10) | 0.723 |
Chlorine (mmol/L) | 106.00 (104.00–108.00) | 105.40 (104.00–107.80) | 0.212 |
FPG (mmol/L) | 5.25 (4.88–5.76) | 5.14 (4.86–5.47) | 0.137 |
ANA-positive (n, %) | 39, 100 | 248, 100 | - |
SSB-positive (n, %) | 20, 51.28 | 121, 48.79 | 0.772 |
nRNP-positive (n, %) | 4, 10.25 | 29, 11.69 | 0.794 |
Scl-70-positive (n, %) | 0, 0 | 1, 0.40 | - |
Jo-1-positive (n, %) | 0, | 0, | - |
rRNP-positive (n, %) | 2, 5.13 | 19, 7.66 | 0.815 |
Systemic lupus erythematosus | 0 | 1, 0.4 | - |
Primary biliary cholangitis | 3, 7.69 | 15, 6.05 | 0.694 |
Autoimmune thyroid diseases | 4, 10.25 | 34, 13.71 | 0.554 |
Raynaud’s phenomenon | 9, 23.08 | 41, 16.53 | 0.317 |