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Table 3 Distribution of characteristics in anti-SSA positive subjects with more than two years follow-up (N = 287)

From: Related factors of renal injury in primary Sjögren's syndrome

 

Renal injury

P value

progression group (N = 39)

non-progression group (N = 248)

Age (years)

54.00 (42.00–65.00)

53.00 (41.00–64.00)

0. 413

Female (n, %)

37, 94.87

232, 93.5

0. 510

Creatinine (μmol/ L)

79.50 (74.25–91.80)

68.95 (61.50–77.85)

 < 0.001

eGFR change (%)

-23.64 (-31.25–-20.42)

4.71(-1.21–13.14)

 < 0.001

Urea (mmol/L)

5.93 (4.80–7.49)

4.96 (4.07–5.96)

 < 0.007

Potassium (mmol/L)

4.00 (3.68–4.31)

4.00 (3.74–4.25)

0. 942

Sodium (mmol/L)

141.20 (138.18–144.00)

141.10 (139.00–143.10)

0.723

Chlorine (mmol/L)

106.00 (104.00–108.00)

105.40 (104.00–107.80)

0.212

FPG (mmol/L)

5.25 (4.88–5.76)

5.14 (4.86–5.47)

0.137

ANA-positive (n, %)

39, 100

248, 100

-

SSB-positive (n, %)

20, 51.28

121, 48.79

0.772

nRNP-positive (n, %)

4, 10.25

29, 11.69

0.794

Scl-70-positive (n, %)

0, 0

1, 0.40

-

Jo-1-positive (n, %)

0,

0,

-

rRNP-positive (n, %)

2, 5.13

19, 7.66

0.815

Systemic lupus erythematosus

0

1, 0.4

-

Primary biliary cholangitis

3, 7.69

15, 6.05

0.694

Autoimmune thyroid diseases

4, 10.25

34, 13.71

0.554

Raynaud’s phenomenon

9, 23.08

41, 16.53

0.317