Fig. 7
From: Transcriptional characteristics and functional validation of three monocyte subsets during aging
Impaired mitochondrial oxidative phosphorylation respiration and enhanced glycolysis of CD14+ monocytes during aging. A. Mitochondrial stress curves of CD14+ monocytes in young (24–26 years, n = 6) and older (62–66 years, n = 6) individuals. B. Comparisons of mitochondrial respiratory parameters of CD14+ monocytes between young (24–26 years, n = 6) and aged (62–66 years, n = 6) individuals. C. Glycolytic rate curves of CD14+ monocytes in young (24–26 years, n = 6) and old (62–66 years, n = 6) individuals. D. Comparisons of glycolytic parameters of CD14+ monocytes between young (24–26 years, n = 6) and elderly (62–66 years, n = 6) individuals. Blue denotes young individuals and orange represents aged individuals, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001