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Fig. 1 | Immunity & Ageing

Fig. 1

From: Bifidobacterium bifidum and Lactobacillus paracasei alleviate sarcopenia and cognitive impairment in aged mice by regulating gut microbiota-mediated AKT, NF-κB, and FOXO3a signaling pathways

Fig. 1

Effects of Bb and Lp on dexamethasone-induced MuRF1 and Atrogin-1/MAFbx expression and LPS-induced TNF-α and IL-6 expression and NF-κB activation in C2C12 cells. Effects on MuRF1 (a) and Atrogin-1/MAFbx expression (b). Effects on TNF-α (c) and IL-6 expression (d) and NF-κB activation (e). C2C12 cells (1 × 105 cells/mL) were treated with dexamethasone (10 µM) or LPS (100 ng/mL) in the absence or presence of Bb, Lp, or LB (1 × 104 colon-forming units [CFUs] /mL and Cr [5 mM]). Data are indicated as mean ± SD (n = 4). #p < 0.05 vs. NC. *p < 0.05 vs. group treated with vehicle with dexamethasone or LPS

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Immunity & Ageing

ISSN: 1742-4933

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