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Fig. 6 | Immunity & Ageing

Fig. 6

From: Bifidobacterium bifidum and Lactobacillus paracasei alleviate sarcopenia and cognitive impairment in aged mice by regulating gut microbiota-mediated AKT, NF-κB, and FOXO3a signaling pathways

Fig. 6

Effects of Bb, Lp, and LB on the gut inflammation in aged mice. Effects on TNF-α (a), IL-6 (b), IL-10 (c), IL-1β (d), and myeloperoxidase (MPO) expression (e), and TNF-α to IL-10 expression ratio (f), and IL-6 to IL-10 expression ratio (g), assessed by qPCR. h Effects on NF-κB+CD11c+ cell population. Bb, Lp, and LB (1 × 109 CFU/mouse/day) and Cr (75 mg/kg) were orally gavaged once a day (6 days in one week) for 8 weeks. Data are indicated as mean ± SD (n = 6). #p < 0.05 vs. Yg. *p < 0.05 vs. Vh/Ag

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