Table 1 Demographic and clinical characteristics of patients with sarcopenia and frailty syndrome and geriatric control
Sarcopenia (N = 12) | Frailty syndrome (N = 36) | Geriatric control (n = 25) | p-value | |
|---|---|---|---|---|
Age (years, mean ± SD) | 77.33 ± 13.75 | 80.50 ± 8.72 | 72.56 ± 13.75 | 0.004* |
Gender | 0.45*** | |||
Women n(%) | 6 (50.00%) | 25 (69.44%) | 17 (68.00%) | |
Men n(%) | 6 (50.00%) | 11 (30.56%) | 8 (31.00%) | |
Mean ± SD | p-value* | |||
ASMM (kg) | 5.95 ± 0.90 | 7.19 ± 0.74 | 7.47 ± 0.80 | < 0.0001 |
FI-CGA | 0.21 ± 0.11 | 0.36 ± 0.09 | 0.14 ± 0.06 | 0.004 |
BMI (kg/m^2) | 23.18 ± 2.97 | 27.61 ± 6.37 | 29.86 ± 5.28 | 0.005 |
Cholesterol (mg/dl) | 194.50 ± 42.75 | 173.85 ± 41.31 | 204.24 ± 42.99 | 0.022 |
Triglycerides (nmol/l) | 105.58 ± 42.91 | 138.74 ± 66.59 | 147.04 ± 60.18 | 0.154 |
LDL (mg/dL) | 100.65 ± 37.64 | 91.06 ± 30.08 | 120.50 ± 37.65 | 0.006 |
Albumin (g/dl) | 4.17 ± 0,38 | 3.98 ± 0.49 | 4.10 ± 0.32 | 0.289 |
Hemoglobin (g/dl) | 12.50 ± 1.60 | 12.11 ± 1.73 | 13.29 ± 1.43 | 0.023 |
LDH (U/L) | 260.52 ± 61.35 | 252.89 ± 103.61 | 229.81 ± 41.67 | 0.443 |
Creatine (µmol/l) | 0.97 ± 0.29 | 0.88 ± 0.24 | 0.89 ± 0.27 | 0.605 |
Vitamin D3 (ng/ml) | 33.75 ± 34.43 | 36.81 ± 29.63 | 35.09 ± 34.88 | 0.850 |
Vitamin B12 (pg/ml) | 455.65 ± 245.43 | 397.72 ± 187.11 | 426.20 ± 243.40 | 0.704 |
Serum Fe level (mcg/dl) | 79.96 ± 10.50 | 61.16 ± 22.84 | 84.11 ± 22.97 | < 0.0001 |
Median (IQR) | P-value** | |||
TUG (s) | 14.50 (11.70, 21.97) | 200.00 (14.75, 26.50) | 14.00 (13.00, 15.00) | < 0.0001 |
ESR (mm/h) | 11.00 (8.00, 15.50) | 22.00 (12.50, 35.25) | 10.00 (8.00, 22.00) | 0.048 |
CRP (mg/dl) | 5.00 (5.00, 6.00) | 7.00 (5.00, 25.50) | 5.00 (5.00, 12.00) | 0.062 |
NT-proBNP (pg/ml) | 354.80 (277.88, 666,57) | 264.30 (163.67, 510.20) | 258.60 (164.60, 559.60) | 0.308 |
CK (U/I) | 67.00 (55.00, 70.79) | 71.00 (45.25, 86.50) | 72.00 (56.00, 106.00) | 0.382 |
N (%) | p-value*** | |||
Osteopenia | 0.009 | |||
Present | 6 (50.00%) | 4 (11.11%) | 2 (8.00%) | |
Not present | 6 (50.00%) | 32 (88.89) | 23 (93.00%) | |
NYHA class | 0.153 | |||
0 | 7 (58.33%) | 27 (75.00%) | 23 (92.00%) | |
I | 0 (0.00%) | 1 (2.78%) | 0 (0.00%) | |
II | 3 (25.00%) | 6 (16.67%) | 1 (4.00%) | |
II-III | 2 (16.67%) | 1 (2.78%) | 1 (4.00%) | |
III | 0 (0.00%) | 1 (2.78%) | 0 (0.00%) | |
Polyarthritis | ||||
Present | 4 (33.33%) | 18 (50.00%) | 13 (52.00%) | 0.574 |
Not present | 8 (66.67%) | 18 (50.00%) | 12 (48.00%) | |
Osteoporosis | ||||
Present | 3 (25.00%) | 9 (25.50%) | 4 (16.00%) | 0.691 |
Not present | 9 (75.00%) | 27 (75.00%) | 21 (84.00%) | |