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Fig. 3 | Immunity & Ageing

Fig. 3

From: Immunological and senescence biomarker profiles in patients after spontaneous clearance of hepatitis C virus: gender implications for long-term health risk

Fig. 3

Study design flowchart. Significant immune checkpoints (ICs) and senescence-associated secretory phenotype (SASP) proteins between subjects who spontaneously cleared HCV versus the control group are shown: A) All individuals, B) Male individuals, C) Female individuals. Statistics: Data were calculated by Generalized Linear Models (GLM) with a gamma distribution (log-link) adjusted by those clinical variables selected following a stepwise method from age, sex, IFN-λ4 genotype (rs12979860), and aspartate transaminase (AST) for A), and by sex, IFN-λ4genotype (rs12979860), and aspartate transaminase (AST) for B) and C), (see Results Section). Abbreviations: ICs, immune checkpoints; SASP, senescence-associated secretory phenotype; SC, spontaneous clearance; C, control

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Immunity & Ageing

ISSN: 1742-4933

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