Fig. 2

Trajectories of serum markers of inflammageing in three age groups and their association with innate cells. In A, four different trajectories could be identified, based on statistical significance (Mann Whitney U) between the age groups. Shown are an example of each trajectory, indicating significant or non-significant differences between the groups, and the other markers that follow this pattern. In B, we show the correlations of circulating monocyte and neutrophil counts with the biomarkers. Shown are the Spearman R coefficients, with color coding according to the strength of the association. *: p < 0.05, ***: p < 0.001, ****: p < 0.0001, ns: not significant