Skip to main content
Fig. 8 | Immunity & Ageing

Fig. 8

From: Hindlimb unloading, a physiological model of microgravity, modifies the murine bone marrow IgM repertoire in a similar manner as aging but less strongly

Fig. 8

Palindromes created by Artemis and nucleotides added by TdT during V(D)J recombination. A Frequencies of sequences without or with palindromic nucleotides at IGHV-IGHD and IGHD-IGHJ junctions in control vs. HU and young vs. aged mice. B Frequencies of sequences according to the number of added nongenomic nucleotides (≤ 6 or ≥ 7 added nucleotides) in control vs. HU and young vs. aged mice. Data are shown as the means ± SDs of 4 groups, each comprising 5 mice (N = 4, n = 5). Statistically significant differences were found using Mann–Whitney or unpaired t tests. *p ≤ 0.05

Back to article page