Fig. 4
From: The effect of metformin on senescence of T lymphocytes
Metformin inhibited the production of proinflammatory cytokine IL-6 in CD3 negative cells. Representative flow analysis of IL-6 production and MFI level in CD3- cells (a), CD3-CD57 + cells (c) and CD3-CD57- cells (d) between 20 mM Met treatment and control for 24 h in middle age group. Representative flow analysis of IL-6 production and MFI in CD3-CD57 + and CD3-CD57- population (b). Expressed as the mean ± SEM. ***P < 0.001; Paired t test. Met, metformin