Fig. 1
From: The role of NLRP3 inflammasome in aging and age-related diseases
Mechanisms and characteristics of cellular senescence. CDK, cyclin-dependent kinase; IL-6, interleukin-6; IL-8, interleukin-8; MMPs, matrix metalloproteinases; mTOR, mechanistic target of rapamycin; Rb, Retinoblastoma protein; SASP, senescence-associated secretory phenotype; SA-β-gal, senescence-associated β-galactosidase