Fig. 4

Association of NLRP3 inflammasome with cancer progression. 5-HT, 5-hydroxytryptamine; ABHD5, α/β-Hydrolase domain-containing protein 5; CRC, colorectal cancer; EMT, epithelial-mesenchymal transition; IL-18, interleukin-18; IL-1β, interleukin-1β; LNCaP, lymph node carcinoma of the prostate; P2Y2R, P2Y purinergic receptor 2; PCa, prostate cell; PC-3, prostate cancer cell line; TAM, tumor-associated macrophage; TGF-β1, transforming growth factor-β1; TNF-α, tumor necrosis factor-α; TRIM59, tripartite motif-containing 59