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Table 1 Demographics of study participants

From: Aging gene signature of memory CD8+ T cells is associated with neurocognitive functioning in Alzheimer’s disease

 

Cognitively Normal (CN)

(N = 38)

Mild Cognitive Impairment (MCI)

(N = 40)

Dementia

(N = 43)

P -value

Age

72.3 ± 8.6

72.7 ± 7.4

71.2 ± 8.2

0.671

Female/Male

23 (60.5%) / 15 (39.5%)

17 (42.5%) / 23 (57.5%)

22 (51.2%) / 21 (48.8%)

0.282

Race

 Non-Hispanic White

22 (57.9%)

31 (77.5%)

40 (93.1%)

0.009

 Black

10 (26.3%)

4 (10%)

1 (2.3%)

 American Indian or Native Alaskan

2 (5.3%)

0

1 (2.3%)

 Asian

1 (2.6%)

1 (2.5%)

0

 Unknown

3 (7.9%)

4 (10%)

1 (2.3%)

Cognitive Scores

 MoCA

25.7 ± 3.2

20.3 ± 4.9

16.1 ± 6.3

 < 0.001

 CDRsob

0.2 ± 0.5

2.2 ± 1.0

5.1 ± 2.3

 < 0.001

  1. Demographic characteristics of 121 Alzheimer’s Disease Research Center (ADRC) participants involved in this study and organized according to clinical group. P-values were obtained by the ANOVA or Chi-square test
  2. Abbreviations: MoCA Montreal Cognitive Assessment, CDRsob Clinical Dementia Rating sum of boxes