Fig. 5

Comparison of the percentage of PD-1 positive cells among different cancer types. (A-D) The percentage of PD-1⁺CD45⁺ cells, PD-1⁺CD3⁺ T cells, PD-1⁺CD3⁺CD4⁺ Th cells, PD-1⁺CD3⁺CD8⁺ CTL in different cancer types including lung cancer (n = 307), esophagus and gastric cancer (n = 212), melanoma (n = 166), colorectal carcinoma (n = 129), kidney cancer (n = 121), gynecological cancer (cervical, ovarian and uterine cancer, n = 94), hepatobiliary cancer (n = 84), breast cancer (n = 66), head and neck cancer (n = 36), bone and soft tissue sarcoma (n = 35), bladder cancer (n = 21), pancreatic cancer (n = 18), lymphoma (n = 14), prostate cancer (n = 13). Data were shown as mean ± SEM and compared by one-way ANOVA test followed by the Turkey test. P values were indicated as follows: *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001