Fig. 1
From: Accelerated immune ageing is associated with COVID-19 disease severity
CD8 T cell subset distribution post-COVID-19 infection. A Gating strategy used to analyse markers subsets within CD4+ve and CD8+ve T cells; naïve (CCR7+veCD45RA+ve); central memory (CCR7+veCD45RA−ve), effector memory (CCR7−veCD45RA−ve) and terminal differentiated effector memory re-expressing RA, EMRA (CCR7−veCD45RA+ve) T cells. Comparison of the systemic percentage of: B CD8 T cells; C Naïve CD8 T cells; D Total memory CD8 T cells; E Central memory CD8 T cells; F Effector memory CD8 T cells G EMRA CD8 T cells. PBMCs were isolated from convalescent COVID-19 patients who had mild (n = 15), moderate (n = 29) and severe (n = 55) disease 3–5 months post-infection, and healthy age and sex-matched controls (n = 59). Data represent individual values, mean (centre bar). Statistical analysis by two-sided Mann–Whitney nonparametric test