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Fig. 4 | Immunity & Ageing

Fig. 4

From: Accelerated immune ageing is associated with COVID-19 disease severity

Fig. 4

The impact of COVID-19 on Regulatory T cells and Th17 cells. A Comparison of systemic percentage of Foxp3+ve CD4 T cells in healthy age and sex-matched controls (n = 59) and mild (n = 15), moderate (n = 29) and severe (n = 55) COVID-19 survivors 3 months post-infection. B Representative flow cytometry plot showing Foxp3+ve regulatory T cells in a healthy control and severe convalescent COVID-19 patients. C Comparison of systemic percentage of RORγt+ve CD4 T cells in healthy age and sex-matched controls (n = 59) and mild (n = 15), moderate (n = 29) and severe (n = 55) COVID-19 survivors 3–5 months post-infection. D Representative flow cytometry plot showing RORγt+ve Th17 cells in a healthy control and severe convalescent COVID-19 patient. E Th17/Treg ratio in healthy age and sex-matched controls (n = 59) and mild (n = 15), moderate (n = 29) and severe (n = 55) COVID-19 survivors 3–5 months post-infection. Statistical analysis by two-sided Mann–Whitney non-parametric test. If not indicated, p value is not significant

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