Fig. 5
From: Accelerated immune ageing is associated with COVID-19 disease severity
B cell subset distribution post-COVID-19. A Gating strategy used to analyse subsets within CD19+ve B cells; naïve (CD27−ve); memory (CD27+ve), regulatory B cells (CD38hiCD24hi) and plasma cells (CD24−veCD38+ve) B cells. B Comparison of systemic percentage of total B cells in healthy age and sex-matched controls (n = 59) and mild (n = 15), moderate (n = 29) and severe (n = 55) COVID-19 survivors 3–5 months post-infection. C Absolute numbers of B cells in healthy age and sex matched controls (n = 39), moderate (n = 14) and severe (n = 46) COVID-19 convalescent patients. Comparison of systemic percentage of (D) memory B cells, (E) Plasma cells, (F) regulatory B cells in healthy age and sex-matched controls (n = 59) and mild (n = 15), moderate (n = 29) and severe (n = 55) COVID-19 survivors 3–5 months post-infection. Statistical analysis by two-sided Mann–Whitney non-parametric test. If not indicated, p-value is not significant