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Table 1 Characteristics of study participants. Variables with normal distribution are described by their mean ± standard deviation (SD) and the differences calculated using an unpaired t test. Variables with non-normal distribution are described by their median and interquartile range (IQR) and the differences calculated using a Mann-Whitney test

From: Immune profiles of pre-frail people living with HIV-1: a prospective longitudinal study

 

All

Robust

Pre-frail

Difference between

pre-frail and non-pre-frail (p)

Sample size, n (%)

46

27 (59%)

19 (41%)

 

Age, years (mean ± SD)

74.4 ± 3.2

73.6 ± 2.6

75.5 ± 3.9

0.058

Female (%)

4

2 (50%)

2 (50%)

0.712

Waist:Hip ratio (mean ± SD)

1.00 ± 0.08

0.98 ± 0.06

1.03 ± 0.10

0.299

Current CD4 count, cells/µL (mean ± SD)

592 ± 245

622 ± 242

550 ± 248

0.335

Current CD4/CD8 ratio (median [IQR])

0.97 [0.64–1.36]

1.01 [0.76–1.44]

0.77 [0.54–1.06]

0.088

Pretherapeutic CD4 count, cells/µL (mean ± SD)

278 ± 171

255 ± 141

308 ± 206

0.353

Duration of infection, years (median [IQR])

24.5 [19.1–26.8]

23.8 [13.7–26.7]

25.0 [23.6–27.2]

0.778

Duration of undetectability, years (mean ± SD)

8.9 ± 7.2

9.3 ± 7.2

8.5 ± 7.4

0.766

Number of comorbidities (median [IQR])

4.0 [3.0–5.0]

4.0 [2.7-5.0]

4.0 [3.0–6.0]

0.288

EPICES score (mean ± SD)

22.8 ± 14.8

19.4 ± 12.9

27.8 ± 16.3

0.071

VACS index score (median [IQR])

39.0 [33.0-47.5]

38.0 [33.0–43.0]

39.0 [33.0–52.0]

0.105