Table 1 Distribution of variables in the two subgroups of PLIC participants classified according to the BPIFB4 genotype
From: Longevity-associated BPIFB4 gene counteracts the inflammatory signaling
BPIFB4 Genotype | ||||
|---|---|---|---|---|
Variables | Others | Homozygous LAV-BPIFB4 | p-value | |
N | 502 | 89 | ||
Sex (Female), % | 69.92 | 56.18 | 0.01 | |
Age, years | 54.66 (8.37) | 54.36 (7.29) | 0.75 | |
BMI | 26.65 (4.29) | 26.30 (3.77) | 0.47 | |
WHR | 0.87 (0.74) | 0.82 (0.05) | 0.24 | |
SBP, mm Hg | 131.27 (15.48) | 130.10 (17.68) | 0.56 | |
DBP, mm Hg | 82.53 (8.66) | 83.15 (9.98) | 0.55 | |
Smoke: former, % | 24.7 | 29.21 | 0.49 | |
Smoke: current, % | 17.93 | 20.22 | ||
Total Cholesterol | 220.59 (38.24) | 227.78 (40.91) | 0.11 | |
HDL-C | 56.89 (14.95) | 54.81 (15) | 0.23 | |
TG** | 89.5 [63–130] | 90 [68–126] | 0.66 | |
LDL-C | 142.5 (35.88) | 151.63 (37.7) | 0.03 | |
apoA1 | 151.1 (24.8) | 148.59 (23.88) | 0.43 | |
apoB | 112.09 (24.33) | 116.85 (26.83) | 0.13 | |
Glucose | 89.63 (13.04) | 90.24 (10.61) | 0.63 | |
Antihypertensive trt, % | 20.92 | 25.84 | 0.3 | |
Antidiabetic trt, % | 1 | 0 | 0.34 | |
Lipid-lowering trt, % | 6.77 | 7.87 | 0.71 | |
Antithrombotic trt, % | 2.19 | 0 | 0.16 | |
Mean IMT | 0.62 (0.12) | 0.64 (0.12) | 0.1 | |
Plaque, % | 0 | 0 | - | |
CHD, % | 0 | 0 | - | |
SCORE < 2, % | 72.26 | 70.79 | 0.76 | |
SCORE 2–5, % | 24.75 | 24.72 | ||
SCORE > = 5, % | 2.99 | 4.49 | ||
Metabolic syndrome % | 21.31 | 21.69 | 0.94 | |