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Fig. 2 | Immunity & Ageing

Fig. 2

From: Changes in the innate immune response to SARS-CoV-2 with advancing age in humans

Fig. 2

Differential secretion of soluble mediators from SARS-CoV-2-stimulated PBMCs 24 h post stimulation. PBMCs were stimulated with irradiated SARS-CoV-2 (IRR) for 24 h. Graphs depict the quantitation of cytokines/chemokines in the supernatant by multiplex. (a) IL-29; (b) IFN-α; (c) TNF-α; (d) IL-6; (e) IL-1Ra; (f) TREM-1; (g) CXCL-10; (h) CCL2; (i) CCL4; (j) CXCL-8. Mean + S.E. Young = 20; Mid-age-20; Aged = 20 subjects. The P value between the control and SARS-CoV-2-stimulated conditions in the three age groups was calculated using the paired t test (parametric). Significance between different age groups was calculated using ordinary one way ANOVA followed by Tukey’s test

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