Figure 3
From: Mycobacterium leprae Hsp65 administration reduces the lifespan of aged high antibody producer mice
Anti-Hsp65 and anti-DNA antibodies production in aged H III female mice. Anti-Hsp65 IgG1 and IgG2a (A), and anti-DNA IgG1 and IgG2a (B) isotype production in the serum of aged mice (3–6 animals/group) inoculated with WT, K409A Hsp65, or PBS (control). Antibody titers were set by ELISA before (day 0) and after 7 and 14 days post Hsp65 inoculation. *p < 0.05 and **p < 0.01 (Two-way ANOVA, Bonferroni multiple comparisons post-test).