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Table 1 Age-dependent decrease of cytokine production

From: Adverse environmental conditions influence age-related innate immune responsiveness

  Dutch   Ghanaian  
  (n = 304) p-value (n = 562) p-value
Change in IL-10 production per 10 years of age (SE)
   LPS -0.117 (0.045) 0.009 -0.053 (0.029) 0.064
   Zymosan n.d.   -0.116 (0.029) < 0.001
   LPS/zymosan n.d.   -0.081 (0.029) 0.006
Change in TNF production per 10 years of age (SE)
   LPS -0.089 (0.041) 0.030 -0.004 (0.028) 0.89
   Zymosan n.d.   -0.025 (0.029) 0.39
   LPS/zymosan n.d.   0.067 (0.030) 0.026
  1. All analyses were adjusted for sex. Estimates indicate the increase in z-scores with standard error per 10 years of age. n.d. not determined