Table 1 Age-dependent decrease of cytokine production
From: Adverse environmental conditions influence age-related innate immune responsiveness
Dutch | Ghanaian | |||
|---|---|---|---|---|
(n = 304) | p-value | (n = 562) | p-value | |
Change in IL-10 production per 10 years of age (SE) | ||||
LPS | -0.117 (0.045) | 0.009 | -0.053 (0.029) | 0.064 |
Zymosan | n.d. | -0.116 (0.029) | < 0.001 | |
LPS/zymosan | n.d. | -0.081 (0.029) | 0.006 | |
Change in TNF production per 10 years of age (SE) | ||||
LPS | -0.089 (0.041) | 0.030 | -0.004 (0.028) | 0.89 |
Zymosan | n.d. | -0.025 (0.029) | 0.39 | |
LPS/zymosan | n.d. | 0.067 (0.030) | 0.026 | |