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Correction: Neo-epitopes emerging in the degenerative hippocampal granules of aged mice can be recognized by natural IgM auto-antibodies

Immunity & Ageing volume 19, Article number: 37 (2022) Cite this article

The Original Article was published on 24 November 2015

Correction: Immun Ageing 12, 23 (2015)

https://doi.org/10.1186/s12979-015-0050-z

Following publication of the original article [1], the authors identified an error in Fig. 1. All the images shown in Fig. 1 (from image A to I) are crops of larger images. To obtain the image G, we mistakenly used the source of the image A instead of the source of the image G. In this new version, the image G has been corrected. The legend of the image remains correct. The correct figure is given below.

Fig. 1
figure 1

Sera from SAMP8, ICR-CD1 and BALB/C mice contain anti-neo-epitope IgMs. Representative images of the hippocampal region of brain sections from 15-month-old ICR-CD1 mice simultaneously stained with Hoechst (blue), anti-MMP-2 antibody (green) and mouse sera (red) from each experimental group as detailed next. a-c: Sera from SAMP8 mice aged 1, 3 and 6 months, respectively. d-g: Sera from ICR-CD1 mice aged 1, 3, 6 and 9 months, respectively. h: Serum from a BALB/C mouse aged 3 months. i: Control staining of the granules with anti-neo-epitope IgMs contained in the OX52 antibody. In all cases the anti-MMP-2 staining showed the clusters of granules. Some granules of the clusters are stained with the serum, indicating that all sera contained anti-neo-epitope IgMs. Scale bar: 50 μm

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Reference

  1. Manich G, Augé E, Cabezón I, et al. Neo-epitopes emerging in the degenerative hippocampal granules of aged mice can be recognized by natural IgM auto-antibodies. Immun Ageing. 2015;12:23. https://doi.org/10.1186/s12979-015-0050-z.

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Authors and Affiliations

  1. Departament de Fisiologia, Facultat de Farmàcia, Universitat de Barcelona, Av. Joan XXIII s/n, 08028, Barcelona, Spain

    Gemma Manich, Elisabet Augé, Itsaso Cabezón, Jordi Vilaplana & Carme Pelegrí

  2. Unitat de Farmacologia I Farmacognòsia, Facultat de Farmàcia, Institut de Biomedicina (IBUB), Universitat de Barcelona, Av. Joan XXIII s/n, 08028, Barcelona, Spain

    Itsaso Cabezón & Mercè Pallàs

  3. CIBERNED Centros de Biomedicina en Red de Enfermedades Neurodegenerativas, Barcelona, Spain

    Mercè Pallàs, Jordi Vilaplana & Carme Pelegrí

Authors
  1. Gemma Manich
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  2. Elisabet Augé
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  3. Itsaso Cabezón
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  4. Mercè Pallàs
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  5. Jordi Vilaplana
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  6. Carme Pelegrí
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Corresponding author

Correspondence to Jordi Vilaplana.

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Manich, G., Augé, E., Cabezón, I. et al. Correction: Neo-epitopes emerging in the degenerative hippocampal granules of aged mice can be recognized by natural IgM auto-antibodies. Immun Ageing 19, 37 (2022). https://doi.org/10.1186/s12979-022-00293-w

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  • DOI: https://doi.org/10.1186/s12979-022-00293-w

Immunity & Ageing

ISSN: 1742-4933

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