Fig. 2

Thymic output and naïve: memory CD4 T cell ratio post-traumatic injury. A Percentage of PTK7⁺ recent thymic emigrants in the naïve CD4 T cell pool in healthy age and sex-matched controls ( n = 55) and traumatic injury patients on day 3 ( n = 54), day 14 ( n = 38), day 28 ( n = 41) and day 60 (n = 16) post-hospital admission B Representative flow cytometry plot showing T cell subsets identified via expression of CCR7 and CD45RA. Peripheral frequency of C CD4RA⁺ CCR7⁺ naïve D Total memory CD4 T cells E CD4RA⁻ CCR7⁺ central memory F CD4RA⁻ CCR7⁻ effector memory G and CD4RA⁺ CCR7.⁻ EMRA CD4 T cells in healthy age and sex-matched controls ( n = 55) and traumatic injury patients on day 3 ( n = 54), day 14 ( n = 38), day 28 ( n = 41) and day 60 ( n = 16) post-hospital admission. The mean value is indicated by the bar. * p < 0.05, ** p < 0.005, *** p < 0.001