Fig. 5

The impact of traumatic injury on B cell subset distribution. A Peripheral numbers of CD19^+ve B cells in healthy age and sex-matched healthy controls (n = 55) and traumatic injury patients on day 3 (n = 49), day 14 (n = 31), day 28 (n = 38) and day 60 (n = 14) post hospital admission B Representative flow cytometry plots showing B cell subsets identified via expression of CD27 and IgD in a healthy control and trauma patient. Frequency of C naïve B cells (IgD⁺ CD27⁻) D switched memory (CD27⁺ IgD⁻) E unswitched memory (CD27⁺ IgD⁺) F regulatory (CD24^hi CD38.^hi) B cells in healthy controls and traumatic injury patients. The mean value is indicated by the bar. * p < 0.05, ** p < 0.005, *** p < 0.001